San Francisco, CA
Therapeutics for combating the increasing bacterial resistance to antibiotics
Acylin Therapeutics Corp.
Small molecule drug development
Agios Pharmaceuticals, Inc.
Cancer therapies addressing cellular metabolism
Enhanced potency, tolerability and pharmacology of protein based therapeutics
Alnylam Holdings, Inc.
RNA interference-based pharmaceuticals
Array BioPharma, Inc.
Chemical intermediate sales and chemistry outsourcing
Mountain View, CA
Live attenuated vaccines including FluMist
Acquired by MedImmune, Inc.
BIND Therapeutics, Inc.
Biopharmaceutical firm developing therapeutic targeted nanoparticles
Bluebird Bio, Inc.
Gene therapies for childhood cerebral adrenoleukodystrophy (CCALD) and beta-thalassemia/sickle cell anemia
Mountain View, CA
Caliper Life Sciences, Inc.
Pioneer in microfluidics ("lab on a chip") for research instrumentation and drug screening
New drug development technology enabling drugs to be switched from injectable to oral, creating new indications or improved labels
Ensemble Therapeutics, Inc.
Chemical synthesis platform using DNA-programmed chemistry to develop synthetic macrocycle drugs called Ensemblins™
La Jolla, CA
Fate Therapeutics, Inc.
Adult stem cell biology
Gene therapy for cardiovascular disease and cancer
Groove BioPharma Corp.
Hua Medicine, Inc.
Sourcing drug discovery technology in U.S. and China
IDUN Pharmaceuticals, Inc.
Discovery of small molecule drugs that interfere with apoptosis
Acquired by Pfizer
Biotherapeutics to address unmet medical needs of critically ill patients
San Diego, CA
Fiber optic arrays for use in genomics
ISB Accelerator Corp.
Building the next generation of biotech companies by providing resources critical to the achievement of scientific proof-of-concept
Woodland Hills, CA
Kythera Biopharmaceuticals, Inc.
Aesthetic and dermatologic prescriptive therapies
Ann Arbor, MI
Mitochondrial biology platform for discovery of small molecules related to diseases/conditions with abnormal cell activity
San Carlos, CA
Treatments for neurodegenerative diseases and behavioral disorders
Acquired by Omeros Corp.
Pharmaco Surgery™ drug platform to reduce trauma from surgical and medical procedures
Cancer therapeutics that disrupt signaling pathways between tumors and the immune system
Permeon Biologics, Inc.
Intracellular biotherapeutics platform to enhance drug delivery
siRNA drug delivery technology
Inhaled therapeutics for respiratory disease and infections
San Diego, CA
GPCR drug discovery and development
Sorbent Therapeutics, Inc.
Fluid-retaining polymers for therapeutics to treat kidney disease and other conditions
Syros Pharmaceuticals, Inc.
Mapping gene regulatory circuits and modulating gene expression factors
Theraclone Sciences, Inc.
Human monoclonal antibody platform with multiple therapeutic product candidates
Trubion Pharmaceuticals, Inc.
Gatineau, Quebec, Canada
VBI Vaccines, Inc.
Vaccine technology platform company enabling the development of thermostable and oral vaccines
VentiRx Pharmaceuticals, Inc.
Developing immunoregulatory therapies based on innate immunity
Virology-based platform for improved identification and validation of cell targets for therapeutic drug development
Xcyte Therapies, Inc.
Palo Alto, CA
Enhanced drug delivery
Monoclonal antibody development platform