Portfolio Companies Include

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908 Devices
Advanced security instrumentation
Boston, MA
Accelerator Corp.
Systems biology incubator
Seattle, WA
Antibiotic therapeutics
San Francisco, CA | NASDAQ: AKAO
Acylin Therapeutics (Acquired)
Small molecule therapeutics
Chicago, IL & WA
Adesto Technologies
Non-volatile memory technology
Santa Clara, CA | NASDAQ: IOTS
Adolor (Acquired)
Analgesic therapeutics
Kenilworth, NJ & PA | NASDAQ: ADLR
Disease and pest resistant crops
Durham, NC
Agios Pharmaceuticals
Gene-targeted cancer therapeutics
Cambridge, MA | NASDAQ: AGIO
Animal feed enzyme
Medford, MA
Agtech Accelerator
Agriculture industry incubator
Durham, NC
Ahura Scientific (Acquired)
Advanced security instrumentation
Waltham, MA
Aira Tech
Assistance service for the visually impaired
San Diego, CA
Accountable care organizations
Bethesda, MD
ALIS (Acquired)
High-resolution microscopy
Peabody, MA
Alnylam Pharmaceuticals
RNAi therapeutics
Cambridge, MA | NASDAQ:  ALNY
Guangzhou, China
Apex Neuro Holdings
Wearable Technology for Personal and Medical Well-Being
Cambridge, MA
ApoGen Biotechnologies
Cancer therapeutics
Seattle, WA
Apropos Technology (Acquired)
Call center software
Oak Brook Terrace, IL | NASDAQ: APRS
Arbor Biotechnologies
Protein Discovery Platform for Therapeutics
Cambridge, MA
Personal health strategies
Seattle, WA
Array Biopharma
Chemistry sales & out-sourcing
Boulder, CO | NASDAQ: ARRY
Aviron (Acquired)
Vaccine therapeutics
Mountain View, CA | NASDAQ: AVIR
Bellerophon Therapeutics
Cardiac therapeutics
BIND Therapeutics
Nanoparticle-targeted therapeutics
Cambridge, MA | NASDAQ: BIND
BlackThorn Therapeutics
CNS pharmaceuticals
San Francisco, CA
Bluebird Bio
Gene therapies
Cambridge, MA | NASDAQ:BLUE
Durham, NC
Boreal Genomics
DNA purification
Vancouver, Canada
Caliper Life Sciences (Acquired)
Microfluidics biomanufacturing
Carrick Therapeutics
Cancer therapeutics
Oxford, Ireland
CelebrateExpress (Acquired)
Web party supply site
Seattle, WA | NASDAQ: BDAY
Oral therapeutics replacement for injectables
Waltham, MA | NASDAQ: CHMA
Ciespace (Acquired)
3D modeling software
Columbia, MD
ClassMates Online (Acquired)
Web alumni host site
Seattle, WA
Codiak Biosciences
Cancer therapeutics
Cambridge, MA
Cooledge Lighting
Solid-state lighting
Richmond, Canada
Crystal IS (Acquired)
Nitride semiconductors
Fowlerville, MI
Cyclacel Pharmaceuticals
Immune system modulating therapeutics
Berkeley Heights, NJ & WA | NASDAQ:  CYCC
Cytrellis Biosystems
Aesthetic medicine
Woburn, MA
Dantz Development (Acquired)
Security software
Hopkinton, MA
deCODE Genetics (Acquired)
Population-based genomics database & diagnostics
Thousand Oaks, CA & Iceland & MA | NASDAQ:  DCGN
Denali Therapeutics
Neurodegenerative therapeutics
San Francisco, CA | NASDAQ:  DNLI
Gene-editing for organ transplantation
Cambridge, MA
Eichrom Technologies (Acquired)
Separations & polymer chemistry
Lisle, IL
Element Genomics
Genomics Discovery Platform
Durham, NC
Protein Sequencing Technology
San Diego, CA
Ensemble Therapeutics
DNA chemical libraries
Cambridge, MA
Everyday Learning (Acquired)
Mathematics curricular materials
Colombus, OH and Chicago, IL
Faraday Pharmaceuticals
Ischemic trauma therapies
Seattle, WA
FastTrack Systems (Acquired)
Clinical trials software
New York, NY & PA
Fate Therapeutics
Stem cell therapeutics
San Diego, CA | NASDAQ: FATE
Genomica (Acquired)
Genomics software systems
Boulder, CO | NASDAQ: GNOM
Genomics Medicine Ireland
Gene-based therapeutics
Dublin, Ireland
Whole-Chromosome Sequencing Platform
Chapel Hill, NC
Cardiovascular gene therapeutics
Gaithersburg, MD | NASDAQ: GNVC
Gossamer Bio
San Diego, CA
Detect cancer early, when it can be cured.
Menlo Park, CA
Homology Medicines
In-vivo gene editing
Bedford, MA
Hua Medicine
Asia-based pharmaceutical development
Shanghai, China
IDUN Pharmaceuticals (Acquired)
Apoptosis therapeutics
San Diego, CA
Ikaria (Acquired)
Critical care respiratory therapeutics
St. Louis, MO & NJ
Diagnostics screening platform
Santa Clara, CA | NASDAQ: ILMN
Celiac Disease Therapies
Cambridge, MA
RFID electronics
Seattle, WA | NASDAQ: PI
ImproveNet, Inc
Web-based home improvement
Redwood City, CA | NASDAQ:  IMPV
Innovalight (Acquired)
Thin film nanotechnology
Palo Alto, CA
Intelligent Reasoning Systems (Acquired)
Optical inspection systems
Austin, TX
Juno Therapeutics
Cancer immunotherapies
Seattle, WA | NASDAQ: JUNO
JUST Biotherapeutics
Therapeutics development & manufacturing
Seattle, WA
JUST Biotherapeutics Asia
Asia-based therapeutics development & manufacturing
Hangzhou, China
Kotura (Acquired)
Silicon photonic chips
Sunnyvale, CA
KSQ Therapeutics
Matching Genomic Function to Diseases
Cambridge, MA
Kura Oncology
Cancer therapeutics
San Diego, CA | NASDAQ: KURA
Kythera Biopharmaceuticals (Acquired)
Aesthetic medicine
Parsippany, NJ & CA | NASDAQ: KYTH
LifeMine Therapeutics
Biosynthetic therapeutics
Cambridge, MA
Tracking RNA via CRISPR Technology
San Diego, CA
Lodo Therapeutics
Therapeutics for Drug Resistant Bacteria
New York, NY
Autoimmune & inflammatory disease therapeutics
Ann Arbor, MI & Plymouth Meeting, MA
Medication control systems & software
San Diego, CA
Metabolic disease therapeutics
San Diego, CA
MicroOptical Devices (Acquired)
Semiconductor surface emitting lasers
Alhambra, CA & NM
Neuropsychiatric treatment using mobile/AI technology
Palo Alto, CA
Movidius (Acquired)
Vision sensing technology
Santa Clara, CA
Nanophase Technologies
Ultra-fine ceramic materials
Romeoville, IL | NASDAQ: NANX
Nano-based materials for electronics/sensors
Milpitas, CA
NetBot (Acquired)
Intelligent agents for online shopping
Redwood City, CA
NeurogesX (Acquired)
Topical hi-dose capsaicin
San Francisco, CA | NASDAQ: NGSX
New Era of Networks (Acquired)
Enterprise application integration & software
Englewood, CO | NASDAQ: NEON
Nexcura (Acquired)
Web portal for health information
New York, New York & WA
NiOptics (Acquired)
Non-imaging optics
Maplewood, MN
Nitronex (Acquired)
Gallium nitride-based power transistors
Santa Clara, CA & NC
Nohla Therapeutics
Universal transplant therapeutics
Seattle, WA
Surgical therapeutics
Seattle, WA | NASDAQ: OMER
Mobile biosensors & diagnostics
San Diego, CA
Petra Pharma
Cancer therapeutics
New York, NY
siRNA-base therapeutics
Seattle, WA | NASDAQ: PZRX
PixelEXX Systems
Chicago, IL
Inhaled respiratory therapeutics
Lexington, MA | NASDAQ: PULM
Digital diagnostics for molecular detection
Lexington, MA | NASDAQ:  QTRX
R2 Technology (Acquired)
Computer-aided diagnostics systems
Marlborough, MA
Receptos (Acquired)
Targeted drug discovery platform
Summit, NJ & CA | NASDAQ: RCPT
Rodeo Therapeutics
Seattle, WA
Rubius Therapeutics
Red cell therapeutics
Cambridge, MA
Sage Therapeutics
CNS therapeutics
Cambridge, MA | NASDAQ: SAGE
Sapphire Energy
Biosynthetic products
San Diego, CA
Scholar Rock
Niche activator therapeutics
Cambridge, MA
Semma Therapeutics
Diabetes therapeutics
Cambridge, MA
Semprius, Inc.
Durham, NC
Sienna Biopharmaceuticals
Aesthetic medicine
Westlake Village, CA | NASDAQ:  SNNA
Siluria Technologies
Chemical manufacturing for natural gas
San Francisco, CA
Singular Genomics Systems
Genomic analysis instrumentation
San Diego, CA
Skyline Vet Pharma
Animal health therapeutics
Research Triangle Park, NC
Syros Pharmaceuticals
Gene-gased cancer therapeutics
Cambridge, MA | NASDAQ: SYRS
Teach.com (Acquired)
Elk Grove Village, IL
Theraclone Sciences
Cancer therapeutics
Seattle, WA
Chemical manufacturing for amino acids
San Francisco, CA
Trubion Pharmaceuticals (Acquired)
Small modular immuno therapeutics
Washington, DC & WA | NASDAQ: TRBN
Twist Bioscience
Synthetic DNA manufacturing
San Francisco, CA
DNA imaging
Cambridge, MA
Unity Biotechnology
Therapeutics for age-related diseases & conditions
San Francisco, CA
Supercomputing grid software
Hoffman Estates, IL
VBI Vaccines
Vaccine therapeutics
Cambridge, MA & Quebec, Canada | NASDAQ: VBIV
VentiRx Pharmaceuticals (Acquired)
Immunoregulatory therapeutics
Summit, NJ & CA
Vir Biotechnology
Perpetual vaccine platform
San Francisco, CA
Vividion Therapeutics
Protein-based therapeutics
San Francisco, CA
Autoimmune & inflammatory disease therapeutics
Seattle, WA
3D printing for electromechanical assemblies
Somerville, MA
WuXiNextCODE Health (Acquired)
Population-based genomics database & diagnostics
Cambridge, MA
Drug delivery vectors
Atlanta, GA | NASDAQ: XNPT
Xtera Communications (Acquired)
Optical amplifiers for long-haul communications