Portfolio Companies Include

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908 Devices
Point-of-need chemical and biomolecular analysis devices
Boston, MA
Abelian Therapeutics
Investigating glia factors in brain disease
Boston, MA
Accelerator Corp.
Systems biology incubator
Seattle, WA
Achaogen
Antibiotic therapeutics
San Francisco, CA | NASDAQ: AKAO
Acylin Therapeutics (Acquired)
Small molecule therapeutics
Chicago, IL & WA
Adesto Technologies
Non-volatile memory technology
Santa Clara, CA | NASDAQ: IOTS
Adolor (Acquired)
Analgesic therapeutics
Kenilworth, NJ & PA | NASDAQ: ADLR
AgBiome
Disease and pest resistant crops
Durham, NC
Agios Pharmaceuticals
Gene-targeted cancer therapeutics
Cambridge, MA | NASDAQ: AGIO
Agrivida
Animal feed enzyme
Medford, MA
Agtech Accelerator
Agriculture industry incubator
Durham, NC
Ahura Scientific (Acquired)
Advanced security instrumentation
Waltham, MA
Aira Tech
Assistance service for the visually impaired
San Diego, CA
Aledade
Accountable care organizations
Bethesda, MD
ALIS (Acquired)
High-resolution microscopy
Peabody, MA
Alnylam Pharmaceuticals
RNAi therapeutics
Cambridge, MA | NASDAQ:  ALNY
AnchorDx
Guangzhou, China
Apex Neuro Holdings
Wearable Technology for Personal and Medical Well-Being
Cambridge, MA
ApoGen Biotechnologies
Cancer therapeutics
Seattle, WA
Apropos Technology (Acquired)
Call center software
Oak Brook Terrace, IL | NASDAQ: APRS
Arbor Biotechnologies
Protein Discovery Platform for Therapeutics
Cambridge, MA
Array Biopharma
Chemistry sales & out-sourcing
Boulder, CO | NASDAQ: ARRY
Aspen Neuroscience
Regenerative medicine focused on Parkinson’s Disease
La Jolla, CA
Aviron (Acquired)
Vaccine therapeutics
Mountain View, CA | NASDAQ: AVIR
Beam Therapeutics
CRISPR base-editing platform
Cambridge, MA
Bellerophon Therapeutics
Cardiac therapeutics
Warren, NJ | NASDAQ: BLPH
BIND Biosciences
Nanoparticle-targeted therapeutics
Cambridge, MA | NASDAQ: BIND
BioPalette
Agricultural gene-editing techniques
Kobe, Japan
BlackThorn Therapeutics
CNS pharmaceuticals
San Francisco, CA
Bluebird Bio
Gene therapies
Cambridge, MA | NASDAQ:BLUE
Boragen
Fungicides
Durham, NC
Boreal Genomics
DNA purification
Vancouver, Canada
Boundless Bio
Therapeutics based on ecDNA discoveries
San Diego, CA
Brii Biosciences
Transforming China's public health
Shanghai, China & San Francisco, CA
Caliper Life Sciences (Acquired)
Microfluidics biomanufacturing
San Jose, CA | NASDAQ: CALP
Carrick Therapeutics
Cancer therapeutics
Oxford, Ireland
CelebrateExpress (Acquired)
Web party supply site
Seattle, WA | NASDAQ: BDAY
Chiasma
Oral therapeutics replacement for injectables
Waltham, MA | NASDAQ: CHMA
Ciespace (Acquired)
3D modeling software
Columbia, MD
ClassMates Online (Acquired)
Web alumni host site
Seattle, WA
Codiak Biosciences
Cancer therapeutics
Cambridge, MA
Cooledge Lighting
Solid-state lighting
Richmond, Canada
Crystal IS (Acquired)
Nitride semiconductors
Fowlerville, MI
CStone Pharmaceuticals
China-based cancer therapeutics
Suzhou, China | HKEX: 2616
Cyclacel Pharmaceuticals
Immune system modulating therapeutics
Berkeley Heights, NJ & WA | NASDAQ:  CYCC
Cytrellis Biosystems
Aesthetic medicine
Woburn, MA
Dantz Development (Acquired)
Security software
Hopkinton, MA
deCODE Genetics (Acquired)
Population-based genomics database & diagnostics
Thousand Oaks, CA & Iceland & MA | NASDAQ:  DCGN
Denali Therapeutics
Neurodegenerative therapeutics
San Francisco, CA | NASDAQ:  DNLI
eGenesis
Gene-editing for organ transplantation
Cambridge, MA
Eichrom Technologies (Acquired)
Separations & polymer chemistry
Lisle, IL
Element Genomics (Acquired)
Genomics Discovery Platform
Durham, NC
Encoded Therapeutics
Precision gene therapies
South San Francisco, CA
Encodia
Protein Analysis Platform
San Diego, CA
Ensemble Therapeutics
DNA chemical libraries
Cambridge, MA
Erasca
Erasing cancer with AI drug discovery platform
San Diego, CA
Everyday Learning (Acquired)
Mathematics curricular materials
Colombus, OH and Chicago, IL
Faraday Pharmaceuticals
Ischemic trauma therapies
Seattle, WA
FastTrack Systems (Acquired)
Clinical trials software
New York, NY & PA
Fate Therapeutics
Stem cell therapeutics
San Diego, CA | NASDAQ: FATE
Genomica (Acquired)
Genomics software systems
Boulder, CO | NASDAQ: GNOM
Genomics Medicine Ireland (Acquired)
Gene-based therapeutics
Dublin, Ireland
Genturi
Whole-Chromosome Sequencing Platform
Chapel Hill, NC
GenVec
Cardiovascular gene therapeutics
Gaithersburg, MD | NASDAQ: GNVC
Glympse Bio
Biological enzyme activity sensors for diagnostics
Cambridge, MA
Gossamer Bio
Therapeutics in immunology, inflammation, and oncology
San Diego, CA | NASDAQ: GOSS
Grail
Detect cancer early, when it can be cured.
Menlo Park, CA
GroundTruth Ag
Soil analysis tools
Research Triangle Park, NC
HiberCell
Therapeutics to prevent cancer relapse and metastasis
New York, NY
Homology Medicines
In-vivo gene editing
Bedford, MA | NASDAQ: FIXX
Hua Medicine
Asia-based pharmaceutical development
Shanghai, China | HKEX: 2552
IDUN Pharmaceuticals (Acquired)
Apoptosis therapeutics
San Diego, CA
Ikaria (Acquired)
Critical care respiratory therapeutics
St. Louis, MO & NJ
Illumina
Diagnostics screening platform
Santa Clara, CA | NASDAQ: ILMN
ImmusanT
Celiac Disease Therapies
Cambridge, MA
Impinj
RFID electronics
Seattle, WA | NASDAQ: PI
ImproveNet, Inc
Web-based home improvement
Redwood City, CA | NASDAQ:  IMPV
Innovalight (Acquired)
Thin film nanotechnology
Palo Alto, CA
Insitro
Machine learning for drug discovery
South San Francisco, CA
Intelligent Reasoning Systems (Acquired)
Optical inspection systems
Austin, TX
Juno Therapeutics (Acquired)
Cancer immunotherapies
Seattle, WA | NASDAQ: JUNO
JUST Biotherapeutics
Therapeutics development & manufacturing
Seattle, WA
JW Therapeutics
China-based cancer therapeutics
Shanghai, China
Karuna Therapeutics
Therapeutics for cognitive impairment
Boston, MA | NASDAQ: KRTX
Kotura (Acquired)
Silicon photonic chips
Sunnyvale, CA
KSQ Therapeutics
Matching Genomic Function to Diseases
Cambridge, MA
Kura Oncology
Cancer therapeutics
San Diego, CA | NASDAQ: KURA
Kythera Biopharmaceuticals (Acquired)
Aesthetic medicine
Parsippany, NJ & CA | NASDAQ: KYTH
LifeMine Therapeutics
Biosynthetic therapeutics
Cambridge, MA
Llama Therapeutics
Thyromimetics drug discovery
San Francisco, CA
Locana
Tracking RNA via CRISPR Technology
San Diego, CA
Lodo Therapeutics
Therapeutics for Drug Resistant Bacteria
New York, NY
Lycera
Autoimmune & inflammatory disease therapeutics
Ann Arbor, MI & Plymouth Meeting, MA
Lyell Immunopharma
Curative cell-based immunotherapeutics for cancer
San Francisco, CA & Seattle, WA
Maze Therapeutics
Targeting genetic modifiers that can protect against disease
San Francisco, CA
MedVantx
Medication control systems & software
San Diego, CA
Metacrine
Metabolic disease therapeutics
San Diego, CA
MicroOptical Devices (Acquired)
Semiconductor surface emitting lasers
Alhambra, CA & NM
Mindstrong
Neuropsychiatric treatment using mobile/AI technology
Palo Alto, CA
Movidius (Acquired)
Vision sensing technology
Santa Clara, CA
Nanophase Technologies
Ultra-fine ceramic materials
Romeoville, IL | NASDAQ: NANX
Nanosys
Nano-based materials for electronics/sensors
Milpitas, CA
NetBot (Acquired)
Intelligent agents for online shopping
Redwood City, CA
NeurogesX (Acquired)
Topical hi-dose capsaicin
San Francisco, CA | NASDAQ: NGSX
New Era of Networks (Acquired)
Enterprise application integration & software
Englewood, CO | NASDAQ: NEON
Nexcura (Acquired)
Web portal for health information
New York, New York & WA
NiOptics (Acquired)
Non-imaging optics
Maplewood, MN
Nitronex (Acquired)
Gallium nitride-based power transistors
Santa Clara, CA & NC
Nohla Therapeutics
Universal transplant therapeutics
Seattle, WA
Novo Vivo
Genomic database services
Palo Alto, CA
Omeros
Surgical therapeutics
Seattle, WA | NASDAQ: OMER
Omniome
SBB DNA sequencing platform
San Diego, CA
Petra Pharma
Cancer therapeutics
New York, NY
PhaseRx
siRNA-base therapeutics
Seattle, WA | NASDAQ: PZRX
PixelEXX Systems
Nanosensors
Chicago, IL
Pulmatrix
Inhaled respiratory therapeutics
Lexington, MA | NASDAQ: PULM
Quanterix
Digital diagnostics for molecular detection
Lexington, MA | NASDAQ:  QTRX
R2 Technology (Acquired)
Computer-aided diagnostics systems
Marlborough, MA
Receptos (Acquired)
Targeted drug discovery platform
Summit, NJ & CA | NASDAQ: RCPT
Rodeo Therapeutics
Seattle, WA
ROME Therapeutics
Therapies to treat renal disease
New York, NY
Rubius Therapeutics
Red cell therapeutics
Cambridge, MA | NASDAQ: RUBY
Sage Therapeutics
CNS therapeutics
Cambridge, MA | NASDAQ: SAGE
Sana Biotechnology
Creating and delivering engineered cells as medicine
Seattle, WA
Sapphire Energy
Biosynthetic products
San Diego, CA
Scholar Rock
Niche activator therapeutics
Cambridge, MA | NASDAQ: SRRK
Semma Therapeutics
Diabetes therapeutics
Cambridge, MA
Semprius, Inc.
Solar cell technology
Durham, NC
Sienna Biopharmaceuticals
Aesthetic medicine
Westlake Village, CA | NASDAQ:  SNNA
Siluria Technologies
Chemical manufacturing for natural gas
San Francisco, CA
Singular Genomics Systems
Genomic analysis instrumentation
San Diego, CA
Sironax
Therapeutics for inflammatory and nero degenerative diseases
Beijing, China
Skyline Vet Pharma
Animal health therapeutics
Research Triangle Park, NC
Syros Pharmaceuticals
Gene-gased cancer therapeutics
Cambridge, MA | NASDAQ: SYRS
Teach.com (Acquired)
Elk Grove Village, IL
Theraclone Sciences
Cancer therapeutics
Seattle, WA
Transcenta Holding
Fully integrated antibody-based biotherapeutics company
Suzhou, China & Boston, MA
Trelys
Chemical manufacturing for amino acids
San Francisco, CA
Trubion Pharmaceuticals (Acquired)
Small modular immuno therapeutics
Washington, DC & WA | NASDAQ: TRBN
Twist Bioscience
Synthetic DNA manufacturing
San Francisco, CA | NASDAQ: TWST
Ultivue
DNA imaging
Cambridge, MA
Unity Biotechnology
Therapeutics for age-related diseases & conditions
San Francisco, CA | NASDAQ: UBX
Univa
Supercomputing grid software
Hoffman Estates, IL
VBI Vaccines
Vaccine therapeutics
Cambridge, MA & Quebec, Canada | NASDAQ: VBIV
VentiRx Pharmaceuticals (Acquired)
Immunoregulatory therapeutics
Summit, NJ & CA
Vindara
Agricultural biotechnology platform
Durham, NC
Vir Biotechnology
Perpetual vaccine platform
San Francisco, CA
Vividion Therapeutics
Protein-based therapeutics
San Francisco, CA
VLST
Autoimmune & inflammatory disease therapeutics
Seattle, WA
Voxel8
3D printing for electromechanical assemblies
Somerville, MA
WuXiNextCODE Genomics (Acquired)
Population-based genomics database & diagnostics
Cambridge, MA
XenoPort
Drug delivery vectors
Atlanta, GA | NASDAQ: XNPT
Xtera Communications (Acquired)
Optical amplifiers for long-haul communications
Allen, TX | NASDAQ: XCOM